Head-to-head comparison

Microsoft Defender for Endpoint vs SentinelOne

Comparing Microsoft Defender for Endpoint and SentinelOne to help you pick the right Endpoint Detection & Response for your needs.

Feature Microsoft Defender for Endpoint SentinelOne
Pricing Paid Paid
Platforms Web Web
Editorial rating ★ 4 / 5 ★ 4.2 / 5
Starting price $3/user/month Contact sales
Community votes 14 14

Microsoft Defender for Endpoint Pros & Cons

  • Built into Windows — no separate agent deployment for Windows environments
  • Lower cost than CrowdStrike or SentinelOne for Microsoft-licensed organizations
  • Deep Microsoft 365 integration for comprehensive Microsoft environment coverage
  • Threat Explorer and Advanced Hunting for investigation
  • Best for Microsoft-heavy environments — less effective for mixed OS environments
  • Detection rates below CrowdStrike and SentinelOne in some third-party tests
  • Less intuitive interface than purpose-built EDR vendors

SentinelOne Pros & Cons

  • Autonomous response rolls back ransomware damage automatically without analyst intervention
  • XDR extends coverage beyond endpoints to cloud, identity, and network
  • One-click remediation reverses malicious changes made by threats
  • Ranger IoT discovery identifies unmanaged devices on the network
  • Enterprise pricing requires sales engagement
  • Autonomous response requires trust in AI decisions
  • Some advanced features require higher-tier licensing

Verdict: Microsoft Defender for Endpoint vs SentinelOne

Microsoft Defender for Endpoint and SentinelOne both serve the Endpoint Detection & Response category well, but suit different priorities. SentinelOne carries the stronger editorial rating (4.2 / 5), Based on community engagement, Microsoft Defender for Endpoint is currently the more widely adopted choice (14 votes), but the better fit ultimately depends on your specific pricing, platform, and feature requirements.

Frequently Asked Questions

Which is cheaper, Microsoft Defender for Endpoint or SentinelOne?
Microsoft Defender for Endpoint and SentinelOne use a similar pricing model (both paid), so the cheaper choice depends on which specific plan tier and feature set you need rather than the base pricing model.
Is Microsoft Defender for Endpoint or SentinelOne rated higher?
SentinelOne has the higher editorial rating at 4.2 out of 5, compared to Microsoft Defender for Endpoint's 4 out of 5. This is Kreemhunt's own staff rating, not a public user aggregate — review the pros and cons below for specifics that matter to your use case.
Which platforms do Microsoft Defender for Endpoint and SentinelOne support?
Microsoft Defender for Endpoint is available on Web. SentinelOne is available on Web. Both tools cover a similar range of platforms.
Can I switch from Microsoft Defender for Endpoint to SentinelOne (or vice versa)?
Most endpoint detection & response tools, including Microsoft Defender for Endpoint and SentinelOne, support data export in standard formats, making migration possible though rarely fully automatic. Expect to manually verify that custom configurations, integrations, and historical data transfer correctly, and budget time for the team to adjust to workflow differences between the two products.
Should I choose Microsoft Defender for Endpoint or SentinelOne?
Microsoft Defender for Endpoint and SentinelOne both serve the Endpoint Detection & Response category well, but suit different priorities. SentinelOne carries the stronger editorial rating (4.2 / 5), Based on community engagement, Microsoft Defender for Endpoint is currently the more widely adopted choice (14 votes), but the better fit ultimately depends on your specific pricing, platform, and feature requirements.